<rdf:RDF
    xmlns:rdf    ="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:rdfs   ="http://www.w3.org/2000/01/rdf-schema#"
    xmlns:daml   ="http://www.daml.org/2001/03/daml+oil#"
    xmlns:xsd    ="http://www.w3.org/2000/10/XMLSchema#"
    xmlns:srdef  ="http://onto.cs.yale.edu:8080/umls/UMLSinDAML/NET/SRDEF#"
>

<!-- This ontology is based on the Semantic Network part of Unified Medical Language System (UMLS)
Knowledge Source Server, which is accessible at http://www.nlm.nih.gov/research/umls/ 
     All the data are retrived from this knowledge sourse server for educational and scietific use
-->
       

<daml:Ontology rdf:about="">
    <daml:versionInfo>$Id: SRDEF.daml Mon Oct 15 21:40:59 2001$</daml:versionInfo> 
    <rdfs:comment>
       Semantic Types of UMLS Semantic Network 
    </rdfs:comment>
    <daml:imports rdf:resource="http://www.daml.org/2001/03/daml+oil"/>
</daml:Ontology>


<daml:Class rdf:ID="Organism">
    <rdfs:comment>
	Generally, a living individual, including all plants and animals.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Plant">
    <rdfs:comment>
	An organism having cellulose cell walls, growing by synthesis of inorganic substances, generally distinguished by the presence of chlorophyll, and lacking the power of locomotion.  Plant parts are included here as well.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Alga">
    <rdfs:comment>
	A chiefly aquatic plant that contains chlorophyll, but does not form embryos during development and lacks vascular tissue.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Fungus">
    <rdfs:comment>
	A eukaryotic organism characterized by the absence of chlorophyll and the presence of a rigid cell wall.  Included here are both slime molds and true fungi such as yeasts, molds, mildews, and mushrooms.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Virus">
    <rdfs:comment>
	An organism consisting of a core of a single nucleic acid enclosed in a protective coat of protein.  A virus may replicate only inside a host living cell.  A virus exhibits some but not all of the usual characteristics of living things.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Rickettsia_or_Chlamydia">
    <rdfs:comment>
	An organism intermediate in size and complexity between a virus and a bacterium, and which is parasitic within the cells of insects and ticks. Included here are all the chlamydias, also called "PLT" for psittacosis- lymphogranuloma venereum-trachoma.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Bacterium">
    <rdfs:comment>
	A small, typically one-celled, prokaryotic micro-organism.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Animal">
    <rdfs:comment>
	An organism with eukaryotic cells, and lacking stiff cell walls, plastids and photosynthetic pigments.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Invertebrate">
    <rdfs:comment>
	An animal which has no spinal column.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Vertebrate">
    <rdfs:comment>
	An animal which has a spinal column.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Amphibian">
    <rdfs:comment>
	A cold-blooded, smooth-skinned vertebrate which characteristically hatches as an aquatic larva, breathing by gills.  When mature, the amphibian breathes with lungs.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Bird">
    <rdfs:comment>
	A vertebrate having a constant body temperature and characterized by the presence of feathers.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Fish">
    <rdfs:comment>
	A cold-blooded aquatic vertebrate characterized by fins and breathing by gills.  Included here are fishes having either a bony skeleton, such as a perch, or a cartilaginous skeleton, such as a shark, or those lacking a jaw, such as a lamprey or hagfish.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Reptile">
    <rdfs:comment>
	A cold-blooded vertebrate having an external covering of scales or horny plates.  Reptiles breathe by means of lungs and are generally egg-laying.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Mammal">
    <rdfs:comment>
	A vertebrate having a constant body temperature and characterized by the presence of hair, mammary glands and sweat glands.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Human">
    <rdfs:comment>
	Modern man, the only remaining species of the Homo genus.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Anatomical_Structure">
    <rdfs:comment>
	A normal or pathological part of the anatomy or structural organization of an organism.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Embryonic_Structure">
    <rdfs:comment>
	An anatomical structure that exists only before the organism is fully formed; in mammals, for example, a structure that exists only prior to the birth of the organism.  This structure may be normal or abnormal.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Congenital_Abnormality">
    <rdfs:comment>
	An abnormal structure, or one that is abnormal in size or location, present at birth or evolving over time as a result of a defect in embryogenesis.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Acquired_Abnormality">
    <rdfs:comment>
	An abnormal structure, or one that is abnormal in size or location, found in or deriving from a previously normal structure.  Acquired abnormalities are distinguished from diseases even though they may result in pathological functioning (e.g., "hernias incarcerate").
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Fully_Formed_Anatomical_Structure">
    <rdfs:comment>
	An anatomical structure in a fully formed organism; in mammals, for example, a structure in the body after the birth of the organism.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Body_System">
    <rdfs:comment>
	A complex of anatomical structures that performs a common function.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Body_Part__Organ__or_Organ_Component">
    <rdfs:comment>
	A collection of cells and tissues which are localized to a specific area or combine and carry out one or more specialized functions of an organism.  This ranges from gross structures to small components of complex organs.  These structures are relatively localized in comparison to tissues.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Tissue">
    <rdfs:comment>
	An aggregation of similarly specialized cells and the associated intercellular substance.  Tissues are relatively non-localized in comparison to body parts, organs or organ components.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Cell">
    <rdfs:comment>
	The fundamental structural and functional unit of living organisms.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Cell_Component">
    <rdfs:comment>
	A part of a cell or the intercellular matrix, generally visible by light microscopy.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Gene_or_Genome">
    <rdfs:comment>
	A specific sequence, or in the case of the genome the complete sequence, of nucleotides along a molecule of DNA or RNA (in the case of some viruses) which represent the functional units of heredity.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Body_Location_or_Region">
    <rdfs:comment>
	An area, subdivision, or region of the body demarcated for the purpose of topographical description.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Body_Space_or_Junction">
    <rdfs:comment>
	An area enclosed or surrounded by body parts or organs or the place where two anatomical structures meet or connect.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Body_Substance">
    <rdfs:comment>
	Extracellular material, or mixtures of cells and extracellular material, produced, excreted, or accreted by the body.  Included here are substances such as saliva, dental enamel, sweat, and gastric acid.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Organism_Attribute">
    <rdfs:comment>
	A property of the organism or its major parts.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Finding">
    <rdfs:comment>
	That which is discovered by direct observation or measurement of an organism attribute or condition, including the clinical history of the patient. The history of the presence of a disease is a 'Finding' and is distinguished from the disease itself.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Laboratory_or_Test_Result">
    <rdfs:comment>
	The outcome of a specific test to measure an attribute or to determine the presence, absence, or degree of a condition.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Injury_or_Poisoning">
    <rdfs:comment>
	A traumatic wound, injury, or poisoning caused by an external agent or force.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Biologic_Function">
    <rdfs:comment>
	A state, activity or process of the body or one of its systems or parts.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Physiologic_Function">
    <rdfs:comment>
	A normal process, activity, or state of the body.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Organism_Function">
    <rdfs:comment>
	A physiologic function of the organism as a whole, of multiple organ systems, or of multiple organs or tissues.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Mental_Process">
    <rdfs:comment>
	A physiologic function involving the mind or cognitive processing.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Organ_or_Tissue_Function">
    <rdfs:comment>
	A physiologic function of a particular organ, organ system, or tissue.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Cell_Function">
    <rdfs:comment>
	A physiologic function inherent to cells or cell components.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Molecular_Function">
    <rdfs:comment>
	A physiologic function occurring at the molecular level.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Genetic_Function">
    <rdfs:comment>
	Functions of or related to the maintenance, translation or expression of the genetic material.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Pathologic_Function">
    <rdfs:comment>
	A disordered process, activity, or state of the organism as a whole, of a body system or systems, or of multiple organs or tissues.  Included here are normal responses to a negative stimulus as well as patholologic conditions or states that are less specific than a disease.  Pathologic functions frequently have systemic effects.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Disease_or_Syndrome">
    <rdfs:comment>
	A condition which alters or interferes with a normal process, state, or activity of an organism.  It is usually characterized by the abnormal functioning of one or more of the host's systems, parts, or organs.  Included here is a complex of symptoms descriptive of a disorder.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Mental_or_Behavioral_Dysfunction">
    <rdfs:comment>
	A clinically significant dysfunction whose major manifestation is behavioral or psychological.  These dysfunctions may have identified or presumed biological etiologies or manifestations.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Cell_or_Molecular_Dysfunction">
    <rdfs:comment>
	A pathologic function inherent to cells, parts of cells, or molecules.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Experimental_Model_of_Disease">
    <rdfs:comment>
	A representation in a non-human organism of a human disease for the purpose of research into its mechanism or treatment.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Event">
    <rdfs:comment>
	A broad type for grouping activities, processes and states.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Activity">
    <rdfs:comment>
	An operation or series of operations that an organism or machine carries out or participates in.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Behavior">
    <rdfs:comment>
	Any of the psycho-social activities of humans or animals that can be observed directly by others or can be made systematically observable by the use of special strategies.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Social_Behavior">
    <rdfs:comment>
	Behavior that is a direct result or function of the interaction of humans or animals with their fellows.  This includes behavior that may be considered anti-social.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Individual_Behavior">
    <rdfs:comment>
	Behavior exhibited by a human or an animal that is not a direct result of interaction with other members of the species, but which may have an effect on others.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Daily_or_Recreational_Activity">
    <rdfs:comment>
	An activity carried out for recreation or exercise, or as part of daily life.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Occupational_Activity">
    <rdfs:comment>
	An activity carried out as part of an occupation or job.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Health_Care_Activity">
    <rdfs:comment>
	An activity of or relating to the practice of medicine or involving the care of patients.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Laboratory_Procedure">
    <rdfs:comment>
	A procedure, method, or technique used to determine the composition, quantity, or concentration of a specimen, and which is carried out in a clinical laboratory.  Included here are procedures which measure the times and rates of reactions.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Diagnostic_Procedure">
    <rdfs:comment>
	A procedure, method, or technique used to determine the nature or identity of a disease or disorder.  This excludes procedures which are primarily carried out on specimens in a laboratory.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Therapeutic_or_Preventive_Procedure">
    <rdfs:comment>
	A procedure, method, or technique designed to prevent a disease or a disorder, or to improve physical function, or used in the process of treating a disease or injury.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Research_Activity">
    <rdfs:comment>
	An activity carried out as part of research or experimentation.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Molecular_Biology_Research_Technique">
    <rdfs:comment>
	Any of the techniques used in the study of or the directed modification of the gene complement of a living organism.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Governmental_or_Regulatory_Activity">
    <rdfs:comment>
	An activity carried out by officially constituted governments, or an activity related to the creation or enforcement of the rules or regulations governing some field of endeavor.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Educational_Activity">
    <rdfs:comment>
	An activity related to the organization and provision of education.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Machine_Activity">
    <rdfs:comment>
	An activity carried out primarily or exclusively by machines.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Phenomenon_or_Process">
    <rdfs:comment>
	A process or state which occurs naturally or as a result of an activity.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Human-caused_Phenomenon_or_Process">
    <rdfs:comment>
	A phenomenon or process that is a result of the activities of human beings.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Environmental_Effect_of_Humans">
    <rdfs:comment>
	A change in the natural environment that is a result of the activities of human beings.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Natural_Phenomenon_or_Process">
    <rdfs:comment>
	A phenomenon or process that occurs irrespective of the activities of human beings.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Entity">
    <rdfs:comment>
	A broad type for grouping physical and conceptual entities.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Physical_Object">
    <rdfs:comment>
	An object perceptible to the sense of vision or touch.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Manufactured_Object">
    <rdfs:comment>
	A physical object made by human beings.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Medical_Device">
    <rdfs:comment>
	A manufactured object used primarily in the diagnosis, treatment, or prevention of physiologic or anatomic disorders.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Research_Device">
    <rdfs:comment>
	A manufactured object used primarily in carrying out scientific research or experimentation.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Conceptual_Entity">
    <rdfs:comment>
	A broad type for grouping abstract entities or concepts.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Idea_or_Concept">
    <rdfs:comment>
	An abstract concept, such as a social, religious or philosophical concept.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Temporal_Concept">
    <rdfs:comment>
	A concept which pertains to time or duration.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Qualitative_Concept">
    <rdfs:comment>
	A concept which is an assessment of some quality, rather than a direct measurement.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Quantitative_Concept">
    <rdfs:comment>
	A concept which involves the dimensions, quantity or capacity of something using some unit of measure, or which involves the quantitative comparison of entities.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Spatial_Concept">
    <rdfs:comment>
	A location, region, or space, generally having definite boundaries.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Geographic_Area">
    <rdfs:comment>
	A geographic location, generally having definite boundaries.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Molecular_Sequence">
    <rdfs:comment>
	A broad type for grouping the collected sequences of amino acids, carbohydrates, and nucleotide sequences.  Descriptions of these sequences are generally reported in the published literature and/or are deposited in and maintained by databanks such as GenBank, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Nucleotide_Sequence">
    <rdfs:comment>
	The sequence of purines and pyrimidines in nucleic acids and polynucleotides.  Included here are nucleotide-rich regions, conserved sequence, and DNA transforming region.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Amino_Acid_Sequence">
    <rdfs:comment>
	The sequence of amino acids as arrayed in chains, sheets, etc., within the protein molecule.  It is of fundamental importance in determining protein structure.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Carbohydrate_Sequence">
    <rdfs:comment>
	The sequence of carbohydrates within polysaccharides, glycoproteins, and glycolipids.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Regulation_or_Law">
    <rdfs:comment>
	An intellectual product resulting from legislative or regulatory activity.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Occupation_or_Discipline">
    <rdfs:comment>
	A vocation, academic discipline, or field of study, or a subpart of an occupation or discipline.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Biomedical_Occupation_or_Discipline">
    <rdfs:comment>
	A vocation, academic discipline, or field of study related to biomedicine.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Organization">
    <rdfs:comment>
	The result of uniting for a common purpose or function.  The continued existence of an organization is not dependent on any of its members, its location, or particular facility.  Components or subparts of organizations are also included here.  Although the names of organizations are sometimes used to refer to the buildings in which they reside, they are not inherently physical in nature.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Health_Care_Related_Organization">
    <rdfs:comment>
	An established organization which carries out specific functions related to health care delivery or research in the life sciences.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Professional_Society">
    <rdfs:comment>
	An organization uniting those who have a common vocation or who are involved with a common field of study.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Self-help_or_Relief_Organization">
    <rdfs:comment>
	An organization whose purpose and function is to provide assistance to the needy or to offer support to those sharing similar problems.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Group">
    <rdfs:comment>
	A conceptual entity referring to the classification of individuals according to certain shared characteristics.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Professional_or_Occupational_Group">
    <rdfs:comment>
	An individual or individuals classified according to their vocation.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Population_Group">
    <rdfs:comment>
	An indivdual or individuals classified according to their sex, racial origin, religion, common place of living, financial or social status, or some other cultural or behavioral attribute.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Family_Group">
    <rdfs:comment>
	An individual or individuals classified according to their family relationships or relative position in the family unit.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Age_Group">
    <rdfs:comment>
	An individual or individuals classified according to their age.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Patient_or_Disabled_Group">
    <rdfs:comment>
	An individual or individuals classified according to a disability, disease, condition or treatment.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Group_Attribute">
    <rdfs:comment>
	A conceptual entity which refers to the frequency or distribution of certain characteristics or phenomena in certain groups.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Chemical">
    <rdfs:comment>
	Compounds or substances of definite molecular composition.  Chemicals are viewed from two distinct perspectives in the network, functionally and structurally.  Almost every chemical concept is assigned at least two types, generally one from the structure hierarchy and at least one from the function hierarchy.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Chemical_Viewed_Structurally">
    <rdfs:comment>
	A chemical or chemicals viewed from the perspective of their structural characteristics.  Included here are concepts which can mean either a salt, an ion, or a compound (e.g., "Bromates" and "Bromides").
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Organic_Chemical">
    <rdfs:comment>
	The general class of carbon-containing compounds, usually based on carbon chains or rings, and also containing hydrogen (hydrocarbons), with or without nitrogen, oxygen, or other elements in which the bonding between elements is generally covalent.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Steroid">
    <rdfs:comment>
	One of a group of polycyclic, 17-carbon-atom, fused-ring compounds occurring both in natural and synthetic forms.  Included here are naturally occurring and synthetic steroids, bufanolides, cardanolides, homosteroids, norsteroids, and secosteroids.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Eicosanoid">
    <rdfs:comment>
	An oxygenated metabolite from polyunsaturated 20 carbon fatty acids including lipoxygenase and cyclooxygenase products and their synthetic analogs. This includes the prostaglandins and thromboxanes.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Nucleic_Acid__Nucleoside__or_Nucleotide">
    <rdfs:comment>
	A complex compound of high molecular weight occurring in living cells. These are basically of two types, ribonucleic (RNA) and deoxyribonucleic (DNA) acids.  Nucleic acids are made of nucleotides (nitrogen-containing base, a 5-carbon sugar, and one or more phosphate group) linked together by a phosphodiester bond between the 5' and 3' carbon atoms.  Nucleosides are compounds composed of a purine or pyrimidine base (usually adenine, cytosine, guanine, thymine, uracil) linked to either a ribose or a deoxyribose sugar.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Organophosphorus_Compound">
    <rdfs:comment>
	An organic compound containing phosphorus as a constituent.  Included here are organic phosphinic, phosphonic and phosphoric acid derivatives and their thiophosphorus counterparts.  Excluded are phospholipids, sugar phosphates, phosphoproteins, nucleotides, and nucleic acids.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Amino_Acid__Peptide__or_Protein">
    <rdfs:comment>
	Amino acids and chains of amino acids connected by peptide linkages.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Carbohydrate">
    <rdfs:comment>
	A generic term that includes monosaccharides, oligosaccharides, and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more terminal group to carboxylic acids, or by replacement of one or more hydroxy groups by a hydrogen atom, an amino group, a thiol group or similar heteroatomic groups.  It also includes derivatives of these compounds.  Included here are sugar phosphates. Excluded are glycolipids and glycoproteins.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Lipid">
    <rdfs:comment>
	An inclusive group of fat or fat-derived substances that are soluble in nonpolar solvents related to fatty acid esters, fatty alcohols, sterols, waxes, etc.  Included in this group are the saponifiable lipids such as glycerides (fats and oils), essential (volatile) oils, and phospholipids.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Chemical_Viewed_Functionally">
    <rdfs:comment>
	A chemical viewed from the perspective of its functional characteristics or pharmacological activities.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Pharmacologic_Substance">
    <rdfs:comment>
	A substance used in the treatment or prevention of pathologic disorders. This includes substances that occur naturally in the body and are administered therapeutically.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Biomedical_or_Dental_Material">
    <rdfs:comment>
	A substance used in biomedicine or dentistry predominantly for its physical, as opposed to chemical, properties.  Included here are biocompatible materials, tissue adhesives, bone cements, resins, toothpastes, etc.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Biologically_Active_Substance">
    <rdfs:comment>
	A generally endogenous substance produced or required by an organism, of primary interest because of its role in the biologic functioning of the organism that produces it.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Neuroreactive_Substance_or_Biogenic_Amine">
    <rdfs:comment>
	An endogenous substance whose activities affect or play an important role in the functioning of the nervous system.  Included here are catecholamines, neuroregulators, neurophysins, etc.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Hormone">
    <rdfs:comment>
	In animals, a chemical usually secreted by an endocrine gland whose products are released into the circulating fluid.  Hormones act as chemical messengers and regulate various physiologic processes such as growth, reproduction, metabolism, etc.  They usually fall into two broad classes, steroid hormones and peptide hormones.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Enzyme">
    <rdfs:comment>
	A complex chemical, usually a protein, that is produced by living cells and which catalyzes specific biochemical reactions.  There are six main types of enzymes: oxidoreductases, transferases, hydrolases, lyases, isomerases, and ligases.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Vitamin">
    <rdfs:comment>
	A substance, usually an organic chemical complex, present in natural products or made synthetically, which is essential in the diet of man or other higher animals.  Included here are vitamin precursors, provitamins, and vitamin supplements.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Immunologic_Factor">
    <rdfs:comment>
	A biologically active substance whose activities affect or play a role in the functioning of the immune system.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Indicator__Reagent__or_Diagnostic_Aid">
    <rdfs:comment>
	A substance primarily of interest for its use in laboratory or diagnostic tests and procedures to detect, measure, examine, or analyze other chemicals, processes, or conditions.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Hazardous_or_Poisonous_Substance">
    <rdfs:comment>
	A substance of concern because of its potentially hazardous or toxic effects.  This would include most drugs of abuse, as well as agents that require special handling because of their toxicity.
    </rdfs:comment>
</daml:Class>


<daml:ObjectProperty rdf:ID="physically_related_to">
    <rdfs:comment>
	Related by virtue of some physical attribute or characteristic.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="part_of">
    <rdfs:comment>
	Composes, with one or more other physical units, some larger whole.  This includes component of, division of, portion of, fragment of, section of, and layer of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="contains">
    <rdfs:comment>
	Holds or is the receptacle for fluids or other substances.  This includes is filled with, holds, and is occupied by.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="location_of">
    <rdfs:comment>
	The position, site, or region of an entity or the site of a process.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="temporally_related_to">
    <rdfs:comment>
	Related in time by preceding, co-occuring with, or following.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="co-occurs_with">
    <rdfs:comment>
	Occurs at the same time as, together with, or jointly.  This includes is co-incident with, is concurrent with, is contemporaneous with, accompanies, coexists with, and is concomitant with.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="precedes">
    <rdfs:comment>
	Occurs earlier in time.  This includes antedates, comes before, is in advance of, predates, and is prior to.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="functionally_related_to">
    <rdfs:comment>
	Related by the carrying out of some function or activity.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="process_of">
    <rdfs:comment>
	Action, function, or state of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="carries_out">
    <rdfs:comment>
	Executes a function or performs a procedure or activity.  This includes transacts, operates on, handles, and executes.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="interacts_with">
    <rdfs:comment>
	Acts, functions, or operates together with.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="practices">
    <rdfs:comment>
	Performs habitually or customarily.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="produces">
    <rdfs:comment>
	Brings forth, generates or creates.  This includes yields, secretes, emits, biosynthesizes, generates, releases, discharges, and creates.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="exhibits">
    <rdfs:comment>
	Shows or demonstrates.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="disrupts">
    <rdfs:comment>
	Alters or influences an already existing condition, state, or situation. Produces a negative effect on.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="causes">
    <rdfs:comment>
	Brings about a condition or an effect.  Implied here is that an agent, such as for example, a pharmacologic substance or an organism, has brought about the effect.  This includes induces, effects, evokes, and etiology.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="prevents">
    <rdfs:comment>
	Stops, hinders or eliminates an action or condition.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="complicates">
    <rdfs:comment>
	Causes to become more severe or complex or results in adverse effects.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="manifestation_of">
    <rdfs:comment>
	That part of a phenomenon which is directly observable or concretely or visibly expressed, or which gives evidence to the underlying process.  This includes expression of, display of, and exhibition of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="affects">
    <rdfs:comment>
	Produces a direct effect on.  Implied here is the altering or influencing of an existing condition, state, situation, or entity.  This includes has a role in, alters, influences, predisposes, catalyzes, stimulates, regulates, depresses, impedes, enhances, contributes to, leads to, and modifies.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="occurs_in">
    <rdfs:comment>
	Takes place in or happens under given conditions, circumstances, or time periods, or in a given location or population.  This includes appears in, transpires, comes about, is present in, and exists in.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="manages">
    <rdfs:comment>
	Administers, or contributes to the care of an individual or group of individuals.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="treats">
    <rdfs:comment>
	Applies a remedy with the object of effecting a cure or managing a condition.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="uses">
    <rdfs:comment>
	Employs in the carrying out of some activity.  This includes applies, utilizes, employs, and avails.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="indicates">
    <rdfs:comment>
	Gives evidence for the presence at some time of an entity or process.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="result_of">
    <rdfs:comment>
	The condition, product, or state occurring as a consequence, effect, or conclusion of an activity or process.  This includes product of, effect of, sequel of, outcome of, culmination of, and completion of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="conceptually_related_to">
    <rdfs:comment>
	Related by some abstract concept, thought, or idea.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="property_of">
    <rdfs:comment>
	Characteristic of, or quality of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="conceptual_part_of">
    <rdfs:comment>
	Conceptually a portion, division, or component of some larger whole.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="evaluation_of">
    <rdfs:comment>
	Judgment of the value or degree of some attribute or process.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="measures">
    <rdfs:comment>
	Ascertains or marks the dimensions, quantity, degree, or capacity of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="diagnoses">
    <rdfs:comment>
	Distinguishes or identifies the nature or characteristics of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="assesses_effect_of">
    <rdfs:comment>
	Analyzes the influence or consequences of the function or action of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="issue_in">
    <rdfs:comment>
	Is an issue in or a point of discussion, study, debate, or dispute.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="associated_with">
    <rdfs:comment>
	has a significant or salient relationship to.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:Class rdf:ID="Substance">
    <rdfs:comment>
	A material with definite or fairly definite chemical composition.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Food">
    <rdfs:comment>
	Any substance generally containing nutrients, such as carbohydrates, proteins, and fats, that can be ingested by a living organism and metabolized into energy and body tissue.  Some foods are naturally occurring, others are either partially or entirely made by humans.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Functional_Concept">
    <rdfs:comment>
	A concept which is of interest because it pertains to the carrying out of a process or activity.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Intellectual_Product">
    <rdfs:comment>
	A conceptual entity resulting from human endeavor.  Concepts assigned to this type generally refer to information created by humans for some purpose.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Language">
    <rdfs:comment>
	The system of communication used by a particular nation or people.
    </rdfs:comment>
</daml:Class>


<daml:ObjectProperty rdf:ID="consists_of">
    <rdfs:comment>
	Is structurally made up of in whole or in part of some material or matter. This includes composed of, made of, and formed of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="adjacent_to">
    <rdfs:comment>
	Close to, near or abutting another physical unit with no other structure of the same kind intervening.  This includes adjoins, abuts, is contiguous to, is juxtaposed, and is close to.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="connected_to">
    <rdfs:comment>
	Directly attached to another physical unit as tendons are connected to muscles.  This includes attached to and anchored to.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="interconnects">
    <rdfs:comment>
	Serves to link or join together two or more other physical units.  This includes joins, links, conjoins, articulates, separates, and bridges.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="surrounds">
    <rdfs:comment>
	Establishes the boundaries for, or defines the limits of another physical structure.  This includes limits, bounds, confines, encloses, and circumscribes.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="traverses">
    <rdfs:comment>
	Crosses or extends across another physical structure or area.  This includes crosses over and crosses through.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="derivative_of">
    <rdfs:comment>
	In chemistry, a substance structurally related to another or that can be made from the other substance.  This is used only for structural relationships. This does not include functional relationships such as metabolite of, by product of, nor analog of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="developmental_form_of">
    <rdfs:comment>
	An earlier stage in the individual maturation of.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="degree_of">
    <rdfs:comment>
	The relative intensity of a process or the relative intensity or amount of a quality or attribute.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="measurement_of">
    <rdfs:comment>
	The dimension, quantity, or capacity determined by measuring.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="method_of">
    <rdfs:comment>
	The manner and sequence of events in performing an act or procedure.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:Class rdf:ID="Sign_or_Symptom">
    <rdfs:comment>
	An observable manifestation of a disease or condition based on clinical judgment, or a manifestation of a disease or condition which is experienced by the patient and reported as a subjective observation.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Classification">
    <rdfs:comment>
	A term or system of terms denoting an arrangement by class or category.
    </rdfs:comment>
</daml:Class>


<daml:ObjectProperty rdf:ID="isa">
    <rdfs:comment>
	The basic hierarchical link in the Network.  If one item "isa" another item then the first item is more specific in meaning than the second item.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="brings_about">
    <rdfs:comment>
	Acts on or influences an entity.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="performs">
    <rdfs:comment>
	Executes, accomplishes, or achieves an activity.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="spatially_related_to">
    <rdfs:comment>
	Related by place or region.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:Class rdf:ID="Anatomical_Abnormality">
    <rdfs:comment>
	An abnormal structure, or one that is abnormal in size or location.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Neoplastic_Process">
    <rdfs:comment>
	A new and abnormal growth of tissue in which the growth is uncontrolled and progressive.  The growths may be malignant or benign.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Receptor">
    <rdfs:comment>
	A specific structure or site on the cell surface or within its cytoplasm that recognizes and binds with other specific molecules.  These include the proteins on the surface of an immunocompetent cell that binds with antigens, or proteins found on the surface molecules that bind with hormones or neurotransmitters and react with other molecules that respond in a specific way.
    </rdfs:comment>
</daml:Class>


<daml:ObjectProperty rdf:ID="analyzes">
    <rdfs:comment>
	Studies or examines using established quantitative or qualitative methods.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:Class rdf:ID="Archaeon">
    <rdfs:comment>
	A member of one of the three domains of life, formerly called Archaebacteria under the taxon Bacteria, but now considered separate and distinct.  Archaea are characterized by: 1) the presence of characteristic tRNAs and ribosomal RNAs; 2) the absence of peptidoglycan cell walls; 3) the presence of ether-linked lipids built from branched-chain subunits; and 4) their occurrence in unusual habitats.  While archaea resemble bacteria in morphology and genomic organization, they resemble eukarya in their method of genomic replication.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Antibiotic">
    <rdfs:comment>
	A pharmacologically active compound produced by growing microorganisms which kill or inhibit growth of other microorganisms.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Element__Ion__or_Isotope">
    <rdfs:comment>
	One of the 109 presently known fundamental substances that comprise all matter at and above the atomic level.  This includes elemental metals, rare gases, and most abundant naturally occurring radioactive elements, as well as the ionic counterparts of elements (NA+, Cl-), and the less abundant isotopic forms.  This does not include organic ions such as iodoacetate to which the type 'Organic Chemical' is assigned.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Inorganic_Chemical">
    <rdfs:comment>
	Chemical elements and their compounds, excluding the hydrocarbons and their derivatives (except carbides, carbonates, cyanides, cyanates and carbon disulfide).  Generally inorganic compounds contain ionic bonds.  Included here are inorganic acids and salts, alloys, alkalies, and minerals.
    </rdfs:comment>
</daml:Class>


<daml:ObjectProperty rdf:ID="branch_of">
    <rdfs:comment>
	Arises from the division of.  For example, the arborization of arteries.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:ObjectProperty rdf:ID="tributary_of">
    <rdfs:comment>
	Merges with.  For example, the confluence of veins.
    </rdfs:comment>
</daml:ObjectProperty>


<daml:Class rdf:ID="Clinical_Drug">
    <rdfs:comment>
	A pharmaceutical preparation as produced by the manufacturer.  The name usually includes the substance, its strength, and the form, but may include the substance and only one of the other two items.
    </rdfs:comment>
</daml:Class>


<daml:Class rdf:ID="Clinical_Attribute">
    <rdfs:comment>
	An observable or measurable property or state of an organism of clinical interest.
    </rdfs:comment>
</daml:Class>


<daml:ObjectProperty rdf:ID="ingredient_of">
    <rdfs:comment>
	Is a component of, as in a constituent of a preparation.
    </rdfs:comment>
</daml:ObjectProperty>


</rdf:RDF>
